Lookup NU author(s): Professor Martin Noble,
Professor Jane Endicott
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Staurosporine exhibits nanomolar IC50 values against a wide range of protein kinases. The structure of a CDK2 strauroporine complex explains the tight binding of this inhibitor and suggests features to be exploited in the design of specific inhibitors of CDKs.
Author(s): Noble MEM; Endicott JA; Lawrie AM; Tunnah P; Brown NR; Johnson LN
Publication type: Letter
Publication status: Published
Journal: Nature Structural Biology
Print publication date: 01/10/1997
ISSN (print): 1072-8368
ISSN (electronic): 1545-9993
Publisher: NATURE PUBLISHING CO