Lookup NU author(s): Dr Dennis Lendrem,
Dr Clare Lendrem
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In the 1990s the pharmaceutical industry sought to increase R&D productivity by shifting development tasks into parallel in order to reduce development cycle times and increase development speed. This paper presents a simple model demonstrating that when attrition rates are high, as in pharmaceutical development, such development speed initiatives can increase the expected time for the first successful molecule to complete development. Increasing the development speed of successful molecules may actually reduce R&D productivity – the Development Speed Paradox.
Author(s): Lendrem D, Lendrem BC
Publication type: Article
Publication status: Published
Journal: Drug Discovery Today
Print publication date: 16/09/2013
ISSN (print): 1741-8364
ISSN (electronic): 1359-6446
Publisher: Elsevier Ltd
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