Lookup NU author(s): Professor Jeff Errington
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The peptidoglycan wall is a defining feature of bacterial cells and was probably already present in their last common ancestor. L-forms are bacterial variants that lack a cell wall and divide by a variety of processes involving membrane blebbing, tubulation, vesiculation and fission. Their unusual mode of proliferation provides a model for primitive cells and is reminiscent of recently developed in vitro vesicle reproduction processes. Invention of the cell wall may have underpinned the explosion of bacterial life on the Earth. Later innovations in cell envelope structure, particularly the emergence of the outer membrane of Gram-negative bacteria, possibly in an early endospore former, seem to have spurned further major evolutionary radiations. Comparative studies of bacterial cell envelope structure may help to resolve the early key steps in evolutionary development of the bacterial domain of life.
Author(s): Errington J
Publication type: Review
Publication status: Published
Journal: Open Biology
Print publication date: 09/01/2013
ISSN (electronic): 2046-2441
Publisher: ROYAL SOC
Notes: Article no. 120143 is 7 pp.