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Mapping Pitch Representation in Neural Ensembles with fMRI

Lookup NU author(s): Professor Tim GriffithsORCiD

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Abstract

Functional magnetic resonance imaging (fMRI) in humans and macaques allows a test of the hypothesis that there is a specialized neural ensemble for pitch within auditory cortex: a pitch center. fMRI measures the blood oxygenation level-dependent (BOLD) response related to regional synaptic activity (Logothetis et al., 2001). The distinction between synaptic activity and spike firing, and species differences encourage caution when comparing BOLD activity in humans and macaques to recordings from single neurons in ferret and marmoset in the previous mini-review. The BOLD data provide support for the pitch-center concept, with ongoing debate about its location.

Publication metadata

Author(s): Griffiths TD, Hall DA

Publication type: Review

Publication status: Published

Journal: Journal of Neuroscience

Year: 2012

Volume: 32

Issue: 39

Pages: 13343-13347

Print publication date: 26/09/2012

ISSN (print): 0270-6474

ISSN (electronic): 1529-2401

Publisher: SOC NEUROSCIENCE

URL: http://dx.doi.org/10.1523/JNEUROSCI.3813-12.2012

DOI: 10.1523/JNEUROSCI.3813-12.2012

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