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Human dendritic cell subsets

Lookup NU author(s): Professor Matthew CollinORCiD, Dr Naomi McGovern, Professor Muzlifah Haniffa

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Abstract

Dendritic cells are highly adapted to their role of presenting antigen and directing immune responses. Developmental studies indicate that DCs originate independently from monocytes and tissue macrophages. Emerging evidence also suggests that distinct subsets of DCs have intrinsic differences that lead to functional specialisation in the generation of immunity. Comparative studies are now allowing many of these properties to be more fully understood in the context of human immunology.

Publication metadata

Author(s): Collin M, McGovern N, Haniffa M

Publication type: Review

Publication status: Published

Journal: Immunology

Year: 2013

Volume: 140

Issue: 1

Pages: 22-30

Print publication date: 12/08/2013

ISSN (print): 0019-2805

ISSN (electronic): 1365-2567

Publisher: WILEY-BLACKWELL

URL: http://dx.doi.org/10.1111/imm.12117

DOI: 10.1111/imm.12117

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