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The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology

Lookup NU author(s): Dr Matthew Pocock, Dr Jennifer Hallinan, Dr Goksel Misirli, Professor Anil Wipat

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Abstract

The re-use of previously validated designs is critical to the evolution of synthetic biology from a research discipline to an engineering practice. Here we describe the Synthetic Biology Open Language (SBOL), a proposed data standard for exchanging designs within the synthetic biology community. SBOL represents synthetic biology designs in a community-driven, formalized format for exchange between software tools, research groups and commercial service providers. The SBOL Developers Group has implemented SBOL as an XML/RDF serialization and provides software libraries and specification documentation to help developers implement SBOL in their own software. We describe early successes, including a demonstration of the utility of SBOL for information exchange between several different software tools and repositories from both academic and industrial partners. As a community-driven standard, SBOL will be updated as synthetic biology evolves to provide specific capabilities for different aspects of the synthetic biology workflow.


Publication metadata

Author(s): Galdzicki M, Clancy KP, Oberortner E, Pocock M, Quinn JY, Rodriguez CA, Roehner N, Wilson ML, Adam L, Anderson JC, Bartley BA, Beal J, Chandran D, Chen J, Densmore D, Endy D, Grunberg R, Hallinan J, Hillson NJ, Johnson JD, Kuchinsky A, Lux M, Misirli G, Peccoud J, Plahar HA, Sirin E, Stan GB, Villalobos A, Wipat A, Gennari JH, Myers CJ, Sauro HM

Publication type: Article

Publication status: Published

Journal: Nature Biotechnology

Year: 2014

Volume: 32

Issue: 6

Pages: 545-550

Print publication date: 06/06/2014

ISSN (print): 1087-0156

ISSN (electronic): 1546-1696

Publisher: Nature Publishing Group

URL: http://dx.doi.org/10.1038/nbt.2891

DOI: 10.1038/nbt.2891


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