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National Cancer Institute, National Heart, Lung and Blood Institute/Pediatric Blood and Marrow Transplantation Consortium First International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: The Need for Pediatric-Specific Long-Term Follow-up Guidelines

Lookup NU author(s): Professor Roderick Skinner

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Abstract

Existing standards for screening and management of late effects occurring in children who have undergone hematopoietic cell transplantation (HCT) include recommendations from pediatric cancer networks and consensus guidelines from adult-oriented transplantation societies applicable to all HCT recipients. Although these approaches have significant merit, they are not pediatric HCT-focused, and they do not address post-HCT challenges faced by children with complex nonmalignant disorders. In this article we discuss the strengths and weaknesses of current published recommendations and conclude that pediatric-specific guidelines for post-HCT screening and management would be beneficial to the long-term health of these patients and would promote late effects research in this field. Our panel of late effects experts also provides recommendations for follow-up and therapy of selected post-HCTorgan and endocrine complications in pediatric patients. Biol Mood Marrow Transplant 18: 334-347 (2012) (C) 2012 American Society for Blood and Marrow Transplantation

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Author(s): Pulsipher MA, Skinner R, McDonald GB, Hingorani S, Armenian SH, Cooke KR, Gracia C, Petryk A, Bhatia S, Bunin N, Nieder ML, Dvorak CC, Sung LL, Sanders JE, Kurtzberg J, Baker KS

Publication type: Article

Publication status: Published

Journal: Biology of Blood and Marrow Transplantation

Year: 2012

Volume: 18

Issue: 3

Pages: 334-347

Print publication date: 01/03/2012

Online publication date: 13/01/2012

Acceptance date: 11/01/2012

ISSN (print): 1083-8791

ISSN (electronic): 1523-6536

Publisher: Elsevier

URL: http://dx.doi.org/10.1016/j.bbmt.2012.01.003

DOI: 10.1016/j.bbmt.2012.01.003

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