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Comparison of regional variability in multi-site photoplethysmographic pulse wave characteristics

Lookup NU author(s): Emeritus Professor Alan MurrayORCiD

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Abstract

The characteristics of the photoplethysmography (PPG) pulse signal depend upon where they an made; with pulses from the various peripheral sites showing differences in amplitude and transit time, and variation of each over time. By studying the pulses obtained simultaneously from 6 peripheral sites (right and left ears, thumbs, and toes), the bilateral and segmental characteristics should allow important information about the peripheral circulation to be extracted. A multisite photoplethysmograaph pulse measurement and analysis system is described which includes a MATLAB-based suite of signal processing algorithms for analysis of the waveforms on a beat-to-beat basis. Multi-site pulse waveforms were collected from 20 normal subjects whilst they performed a slow paced breathing exercise at I breath every 10 s for 300 s. In this study the PPG pulse waveform characteristics at the 3 segmental levels (right and left ears, thumbs, and toes) were assessed using two types of analysis; pulse amplitude and its variability, and pulse transit time and its variability. The mean calibrated pulse amplitudes were tin arbitrary units!; ears (0.023), thumbs (0.043), and toes (0.013), with coefficients of variability; ears and thumbs 14%, and toes 20%. A significant difference in pulse transit time of 4 ms between the right and left toes was detected (right lagging left, P<0.01). The mean overall pulse transit times were; ears (0.133 s), thumbs (0. 199 s), and toes (0.302 s), with coefficients of variability; ears 2.6%, thumbs 1.9%, and toes 2.1%. In this study we have utilized signal processing algorithms to calculate on a beat-to-beat basis measures of pulsatility and determine a set of normative data for our multi-site pulse system.


Publication metadata

Author(s): Allen J, Murray A

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: FIRST INTERNATIONAL CONFERENCE ON ADVANCES IN MEDICAL SIGNAL AND INFORMATION PROCESSING

Year of Conference: 2000

Pages: 26-31

Publisher: INST ELECTRICAL ENGINEERS INSPEC INC

Library holdings: Search Newcastle University Library for this item

ISBN: 0852967284


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