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Incidence and Prevalence of Unrecognized Myocardial Infarction in People With Diabetes: A substudy of the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study

Lookup NU author(s): Emeritus Professor Philip Home

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Abstract

OBJECTIVE-To examine the prevalence and incidence of unrecognized myocardial infarction in a contemporary population with type 2 diabetes.RESEARCH DESIGN AND METHODS-We performed a retrospective analysis of the electrocardiograms (ECGs) recorded at baseline and after 2 years for the first 1,004 type 2 diabetic individuals to be randomized in the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study.RESULTS-ECGs suitable for analysis were obtained from 669 participants. The prevalence of unrecognized Q-wave myocardial infarction at baseline was 1.9% (n = 13). The incidence of unrecognized Q-wave myocardial infarction at the end of 2 years of follow-up was 1.5/1,000-person-years (n = 2). One-third (13 of 39) of prevalent and one-quarter (2 of 8) of incident myocardial infarctions were unrecognized.CONCLUSIONS-Although the prevalence and incidence of myocardial infarction was low, unrecognized Q-wave myocardial infarctions made up a substantial proportion of all events.

Publication metadata

Author(s): MacDonald MR, Petrie MC, Home PD, Komajda M, Jones NP, Beck-Nielsen H, Gomis R, Hanefeld M, Pocock SJ, Curtis PS, McMurray JJV

Publication type: Article

Publication status: Published

Journal: Diabetes Care

Year: 2011

Volume: 34

Issue: 6

Pages: 1394-1396

Print publication date: 11/05/2011

Date deposited: 13/08/2014

ISSN (print): 0149-5992

ISSN (electronic): 1935-5548

Publisher: American Diabetes Association

URL: http://dx.doi.org/10.2337/dc10-2398

DOI: 10.2337/dc10-2398

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