Lookup NU author(s): Dr Soren Nielsen,
Professor Nikolay Zenkin
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Arimbasseri et al., in their Comment, suggest that to terminate transcription in vivo, RNA polymerase III uses a mechanism other than hairpin-dependent termination and that properties of purified polymerase may depend on preparation procedure. Evidence suggests that our preparation is indeed different from that of other methods. Our new data suggest that, apart from hairpin-dependent termination, one or more "fail-safe" termination mechanisms may exist in the cell.
Author(s): Nielsen S, Zenkin N
Publication type: Editorial
Publication status: Published
Print publication date: 01/08/2014
Acceptance date: 30/06/2014
ISSN (print): 0036-8075
ISSN (electronic): 1095-9203
Publisher: American Association for the Advancement of Science