Lookup NU author(s): Professor Rita Horvath,
Professor Patrick Chinnery
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Protein synthesis is critically dependent on transfer (t)-RNAs, but the factors regulating tRNA function are poorly understood. In this issue of Cell Metabolism, Wei et al. (2015) show that Cdk5 regulatory subunit-associated protein-like-1 synchronizes mitochondrial and cytosolic translation in response to external stress, providing key insight into the pathogenesis of a common inherited mitochondrial disease.
Author(s): Horvath R, Chinnery PF
Publication type: Editorial
Publication status: Published
Journal: Cell Metabolism
Print publication date: 03/03/2015
Online publication date: 03/03/2015
ISSN (print): 1550-4131
ISSN (electronic): 1932-7420
Publisher: Cell Press