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Extracellular DNA in oral microbial biofilms

Lookup NU author(s): Dr Nicholas Jakubovics, Professor Grant Burgess

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Abstract

The extracellular matrix of microbial biofilms is critical for surface adhesion and nutrient homeostasis. Evidence is accumulating that extracellular DNA plays a number of important roles in biofilm integrity and formation on hard and soft tissues in the oral cavity. Here, we summarise recent developments in the field and consider the potential of targeting DNA for oral biofilm control. (C) 2015 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.


Publication metadata

Author(s): Jakubovics NS, Burgess JG

Publication type: Article

Publication status: Published

Journal: Microbes and Infection

Year: 2015

Volume: 17

Issue: 7

Pages: 531-537

Print publication date: 01/07/2015

Online publication date: 08/04/2015

Acceptance date: 26/03/2015

ISSN (print): 1286-4579

ISSN (electronic): 1769-714X

Publisher: Elsevier

URL: http://dx.doi.org/10.1016/j.micinf.2015.03.015

DOI: 10.1016/j.micinf.2015.03.015


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