Lookup NU author(s): Dr Fahimeh Dehkhoda,
Dr Ahmed Abd El-Aal,
Dr Reza Ramezani,
Dr Patrick Degenaar
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Implantable neuro-prosthetics have provided considerable clinical benefit to a range of neurological conditions. Optogenetics is a particular recent interest which utilizes high radiance light for photo-activation of genetically altered nerve cells. This can provide improved biocompatibility and neural targeting over electrical stimuli. To date the primary optical delivery method in tissue for optogenetics has been via optic fibre which makes large scale multiplexing difficult. An alternative approach is to incorporate optical micro-emitters directly on implantable probes but this still requires electrical multiplexing. In this work, we demonstrate a fully active optoelectronic probe utilizing industry standard 0.35 mu m CMOS technology, capable of both light delivery and electrical recording. The incorporation of electronic circuits onto the device further allows us to incorporate smart sensors to determine diagnostic state to explore long term viability during chronic imlantation.
Author(s): Dehkhoda F, Soltan A, Ramezani R, Zhao H, Liu Y, Constandinou T, Degenaar P
Publication type: Conference Proceedings (inc. Abstract)
Publication status: Published
Conference Name: 2015 IEEE Sensors
Year of Conference: 2015
Print publication date: 01/01/2015
Online publication date: 07/01/2016
Acceptance date: 01/01/1900
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