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Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration

Lookup NU author(s): Professor Anthony De SoyzaORCiD

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Abstract

Bronchiectasis is a disease of renewed interest in light of an increase in prevalence and increasing burden on international healthcare systems. There are no licensed therapies, and large gaps in knowledge in terms of epidemiology, pathophysiology and therapy. The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) is a European Respiratory Society (ERS) Clinical Research Collaboration, funded by ERS to promote high-quality research in bronchiectasis. The objective of this consensus statement was to define research priorities in bronchiectasis. From 2014 to 2015, EMBARC used a modified Delphi process among European bronchiectasis experts to reach a consensus on 55 key research priorities in this field. During the same period, the European Lung Foundation collected 711 questionnaires from adult patients with bronchiectasis and their carers from 22 European countries reporting important research priorities from their perspective. This consensus statement reports recommendations for bronchiectasis research after integrating both physicians and patients priorities, as well as those uniquely identified by the two groups. Priorities identified in this consensus statement provide the clearest possible roadmap towards improving our understanding of the disease and the quality of care for patients with bronchiectasis.


Publication metadata

Author(s): Aliberti S, Masefield S, Polverino E, De Soyza A, Loebinger MR, Menendez R, Ringshausen FC, Vendrell M, Powell P, Chalmers JD, EMBARC Study Group

Publication type: Article

Publication status: Published

Journal: European Respiratory Journal

Year: 2016

Volume: 48

Issue: 3

Pages: 632-647

Print publication date: 01/09/2016

Acceptance date: 02/03/2016

ISSN (print): 0903-1936

ISSN (electronic): 1399-3003

Publisher: European Respiratory Journal

URL: http://dx.doi.org/10.1183/13993003.01888-2015

DOI: 10.1183/13993003.01888-2015


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Funding

Funder referenceFunder name
European Respiratory Society as Clinical Research Collaboration
Wellcome Trust
115721Inhaled Antibiotics in Bronchiectasis and Cystic Fibrosis consortium, a project of the European Union Innovative Medicines Initiative

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