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Lookup NU author(s): Dr Alwin GieselmannORCiD, Professor Alexander Thiele
This is the authors' accepted manuscript of an article that has been published in its final definitive form by American Association for the Advancement of Science, 2016.
For re-use rights please refer to the publisher's terms and conditions.
Neocortical activity is permeated with endogenously generated fluctuations, but how these dynamics affect goal-directed behavior remains a mystery. We found that ensemble neural activity in primate visual cortex spontaneously fluctuated between phases of vigorous (On) and faint (Off) spiking synchronously across cortical layers. These On-Off dynamics, reflecting global changes in cortical state, were also modulated at a local scale during selective attention. Moreover, the momentary phase of local ensemble activity predicted behavioral performance. Our results show that cortical state is controlled locally within a cortical map according to cognitive demands and reveal the impact of these local changes in cortical state on goal-directed behavior.
Author(s): Engel TA, Steinmetz NA, Gieselmann MA, Thiele A, Moore T, Boahen K
Publication type: Article
Publication status: Published
Journal: Science
Year: 2016
Volume: 354
Issue: 6316
Pages: 1140-1144
Print publication date: 02/12/2016
Acceptance date: 31/10/2016
Date deposited: 02/02/2017
ISSN (print): 0036-8075
ISSN (electronic): 1095-9203
Publisher: American Association for the Advancement of Science
URL: http://dx.doi.org/10.1126/science.aag1420
DOI: 10.1126/science.aag1420
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