Lookup NU author(s): Craig Gerrand,
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© 2014 Springer-Verlag London. All rights are reserved. Background This is a retrospective study of 600 patients with pathologically verifi ed osteogenic sarcoma (excluding tumours of the jaws and parosteal osteogenic sarcoma). Methodology Four hundred and eight were traced for 5-year follow-up of whom eighty-three (20.3 %) survived more than 5 years. Results The survival rate (17.1 %) for patients whose tumours were predominantly osteoblastic was lower, but not to a statistically signifi cant degree, than the rate for those with chondroblastic or fi broblastic tumours. Over 25 % of those with tumours in the more readily treatable sites, namely distal to the proximal end of the humerus or femur, survived 5 years. The more anaplastic sarcomata were associated with a poorer prognosis than the average, but the difference was not statistically signifi cant. Two patients survived long intervals after resection for pulmonary metastasis. Twenty patients had osteogenic sarcoma that developed in lesions of Paget's disease with three surviving for long periods. Sixteen had osteogenic sarcoma that arose in bones that had been irradiated previously all with survival of less than 3 years. Conclusions It is concluded that vigorous, prompt treatment should be employed for osteogenic sarcoma, which may result in a gratifying number of survivors obtained.
Author(s): Gerrand CH, Rankin K
Publication type: Book Chapter
Publication status: Published
Book Title: Classic Papers in Orthopaedics
Print publication date: 01/01/2014
Online publication date: 07/12/2013
Acceptance date: 01/01/1900
Place Published: London
Library holdings: Search Newcastle University Library for this item