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STAT2

Lookup NU author(s): Professor Sophie Hambleton

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Abstract

© 2014 Elsevier Inc. All rights reserved. Human STAT2 deficiency is a rare autosomal recessive disorder of innate immunity, with apparently variable clinical penetrance. It confers unique susceptibility to viral infection, including vaccine strain measles, by preventing the normal transcriptional response to innate interferon.


Publication metadata

Author(s): Hambleton S

Publication type: Book Chapter

Publication status: Published

Book Title: Stiehm's Immune Deficiencies

Year: 2014

Pages: 721-725

Online publication date: 15/08/2014

Acceptance date: 01/01/1900

Publisher: Academic Press

Place Published: Amsterdam

URL: https://doi.org/10.1016/B978-0-12-405546-9.00036-4

DOI: 10.1016/B978-0-12-405546-9.00036-4

Library holdings: Search Newcastle University Library for this item

ISBN: 9780124058606


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