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Lookup NU author(s): Professor Quentin Anstee
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© Royal College of Physicians 2015. All rights reserved.Alcoholic liver disease (ALD) and, increasingly, non-alcoholic fatty liver disease (NAFLD) are common causes of advanced liver disease in many developed countries including the UK. Both diseases share parallel natural histories, progressing from steatosis, to steatohepatitis and fibrosis/cirrhosis; and are characterised by substantial interindividual variation in disease outcome. This article will provide an overview of disease mechanisms, genetic modifiers and management, focusing principally on NAFLD, while drawing parallels between the two conditions where appropriate.
Author(s): Rowell RJ, Anstee QM
Publication type: Review
Publication status: Published
Journal: Clinical Medicine, Journal of the Royal College of Physicians of London
Print publication date: 01/12/2015
Acceptance date: 01/01/1900
ISSN (print): 1470-2118
ISSN (electronic): 1473-4893
Publisher: Royal College of Physicians