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Engineering bacterial populations for pattern formation

Lookup NU author(s): Professor Anil Wipat, Dr Jennifer Hallinan

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Abstract

© 2016 IEEE. The automated design of synthetic biological circuits is an active area of research. A particularly promising area of research is the engineering of populations of communicating bacteria, in order to produce behaviour more complex than is possible with the engineering of individual bacteria. We present a computational approach to the engineering of communicating bacterial populations, using a multi-level approach. Circuits are designed using an evolutionary algorithm, at a high level of abstraction, with an agent-based model. Evolved agents can then be mapped onto previously-defined, lower-level components such as Standard Virtual Parts. This approach is applied to the evolution of a two-dimensional pattern, the French Flag.


Publication metadata

Author(s): Sutantyo D, Walker C, Debono N, Vargas J, Wipat A, Hallinan JS

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: CIBCB 2016 - Annual IEEE International Conference on Computational Intelligence in Bioinformatics and Computational Biology

Year of Conference: 2016

Online publication date: 02/01/2017

Acceptance date: 02/04/2016

Publisher: IEEE

URL: http://doi.org/10.1109/CIBCB.2016.7758116

DOI: 10.1109/CIBCB.2016.7758116

Library holdings: Search Newcastle University Library for this item

ISBN: 9781467394727


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