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The role of whey protein in postprandial glycaemic control

Lookup NU author(s): Professor Emma Stevenson, Dr Dean Allerton

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Abstract

Copyright © The Authors 2017 Epidemiological studies demonstrate that poor glycaemic control is an independent risk factor for CVD. Postprandial glycaemia has been demonstrated as a better predictor of glycated Hb, the gold standard of glycaemic control, when compared with fasting blood glucose. There is a need for more refined strategies to tightly control postprandial glycaemia, particularly in those with type 2 diabetes, and nutritional strategies around meal consumption may be effective in enhancing subsequent glycaemic control. Whey protein administration around meal times has been demonstrated to reduce postprandial glycaemia, mediated through various mechanisms including an enhancement of insulin secretion. Whey protein ingestion has also been shown to elicit an incretin effect, enhancing the secretion of glucose-dependent insulinotropic peptide and glucagon-like peptide-1, which may also influence appetite regulation. Acute intervention studies have shown some promising results however many have used large dosages (50–55 g) of whey protein alongside high-glycaemic index test meals, such as instant powdered potato mixed with glucose, which does not reflect realistic dietary strategies. Long-term intervention studies using realistic strategies around timing, format and amount of whey protein in relevant population groups are required.


Publication metadata

Author(s): Stevenson EJ, Allerton DM

Publication type: Article

Publication status: Published

Journal: Proceedings of the Nutrition Society

Year: 2018

Volume: 77

Issue: 1

Pages: 42-51

Print publication date: 01/02/2018

Online publication date: 25/09/2017

Acceptance date: 02/04/2016

ISSN (print): 0029-6651

ISSN (electronic): 1475-2719

Publisher: Cambridge University Press

URL: https://doi.org/10.1017/S0029665117002002

DOI: 10.1017/S0029665117002002


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