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SynBioHub: A Standards-Enabled Design Repository for Synthetic Biology

Lookup NU author(s): James Alastair McLaughlin McLaughlin, Professor Christopher Myers, Zach Zundel, Dr Goksel Misirli, Dr Dana OfiteruORCiD, Dr Angel Goni-Moreno, Professor Anil Wipat

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This is the authors' accepted manuscript of an article that has been published in its final definitive form by American Chemical Society, 2018.

For re-use rights please refer to the publisher's terms and conditions.


Abstract

The SynBioHub repository (https://synbiohub.org) is an open-source software project which facilitates the sharing of information about engineered biological systems. SynBioHub provides computational access for software and data integration, and a graphical user interface that enables users to search for and share designs in a Web browser. By connecting to relevant repositories (e.g. the iGEM repository, JBEI ICE, and other instances of SynBioHub), the software allows users to browse, upload, and download data in various standard formats, regardless of their location or representation. SynBioHub also provides a central reference point for other resources to link to, delivering design information in a standardized format using the Synthetic Biology Open Language (SBOL). The adoption and use of SynBioHub, a community-driven effort, has the potential to overcome the reproducibility challenge across laboratoriesby helping to address the current lack of information about published designs.


Publication metadata

Author(s): McLaughlin JA, Myers CJ, Zundel Z, Misirli G, Zhang M, Ofiteru ID, Goni-Moreno A, Wipat A

Publication type: Article

Publication status: Published

Journal: ACS Synthetic Biology

Year: 2018

Volume: 7

Issue: 2

Pages: 682-688

Print publication date: 16/02/2018

Online publication date: 09/01/2018

Acceptance date: 08/01/2018

Date deposited: 17/01/2018

ISSN (electronic): 2161-5063

Publisher: American Chemical Society

URL: http://pubs.acs.org/doi/abs/10.1021/acssynbio.7b00403

DOI: 10.1021/acssynbio.7b00403


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Funding

Funder referenceFunder name
EP/J02175X/1
EP/N031962/1EPSRC
EP/R019002/1EPSRC

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