Lookup NU author(s): Maciek Misiura,
Dr Joao Filipe,
Professor Ilias Kyriazakis
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
Calcium (Ca) digestibility and utilisation in growing pigs are not well understood, and are usually neglected in diet formulation. This has implications not only for the accurate determination of its requirements, but also for its interactions with other nutrients. A systematic review and meta-analysis (meta-regression) of published trials were carried out to quantify factors affecting Ca absorption and utilisation, and to derive an estimate of Ca endogenous excretion. The analysis was carried out on the data from 40 studies, corresponding to 201 treatments performed on 1204 pigs. The results indicated that whilst Ca absorption and retention (g/kg of BW per day) increased with increasing Ca intake (p<0.001), non-phytate-Phosphorus intake (p<0.001) and exogenous phytase supplementation (p<0.001), these values decreased with increasing phytate-Phosphorus intake (p<0.05). Interactions between exogenous phytase and Ca intake indicating reduced efficacy of this enzyme (p<0.001), and between phytate-Phosphorus intake and exogenous phytase, counteracting the direct negative effect of phytate-Phosphorous (p<0.05) on Ca absorption and retention, were also detected. There were no effects of animal-related characteristics, such as pig genotype in Ca absorption and retention. The large amount of variance explained in Ca absorption (90%) and retention (91%) supported our choice of independent variables. Endogenous Ca losses obtained via linear regression were 239 mg/kg of DMI (95% CI 114, 364). These outcomes advance the current understanding of Ca digestibility and utilisation, and should contribute towards establishing requirements for digestible Ca. Consequently, pig diets will be more correctly formulated if digestible Ca values are used in estimating requirements for Ca.
Author(s): Misiura MM, Filipe JAN, Walk CL, Kyriazakis I
Publication type: Article
Publication status: Published
Journal: British Journal of Nutrition
Print publication date: 14/06/2018
Online publication date: 03/04/2018
Acceptance date: 14/02/2018
ISSN (print): 0007-1145
ISSN (electronic): 1475-2662
Publisher: Cambridge University Press
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