Toggle Main Menu Toggle Search

ePrints

Robotic lateral oropharyngectomy following diagnostic tonsillectomy is oncologically safe in patients with high risk human papillomavirus related squamous cell cancer

Lookup NU author(s): Dr Hans Sathasivam, James O'Hara, Dr David Meikle, Dr Charles Kelly, Dr Max Robinson, Professor Vinidh Paleri

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Abstract

© 2018 Springer-Verlag GmbH Germany, part of Springer Nature Purpose: Diagnostic tonsillectomy is rarely an oncologic operation owing to close or positive margins. The standard of care is for further treatment to the primary site, typically with adjuvant radiotherapy. Methods: 14 patients with close or positive margins following a diagnostic tonsillectomy underwent transoral robotic surgery (TORS) and lateral oropharyngectomy; five patients with the longest follow-up had their excision specimens examined with a step serial sectioning technique (SSS). Results: Conventional histopathological examination of the TORS resection specimens did not demonstrate residual carcinoma in 13 patients, confirmed by examination using SSS in 5 patients. There were no post-operative complications or long-term functional deficit. Seven patients received surgery alone with 100% overall and disease specific survival, respectively (median follow-up 27.5 months; range 5.2–50.4). Conclusions: This prospective study suggests that TORS lateral oropharyngectomy alone is an oncologically safe treatment when close or positive margins are identified on diagnostic tonsillectomy in HPV-positive SCC.


Publication metadata

Author(s): Siddiq S, Cartlidge D, Stephen S, Sathasivam HP, Fox H, O'Hara J, Meikle D, Iqbal MS, Kelly CG, Robinson M, Paleri V

Publication type: Article

Publication status: Published

Journal: European Archives of Oto-Rhino-Laryngology

Year: 2018

Volume: 275

Issue: 7

Pages: 1853-1860

Print publication date: 01/07/2018

Online publication date: 12/05/2018

Acceptance date: 06/04/2018

ISSN (print): 0937-4477

ISSN (electronic): 1434-4726

Publisher: Springer Verlag

URL: https://doi.org/10.1007/s00405-018-4968-6

DOI: 10.1007/s00405-018-4968-6


Altmetrics

Altmetrics provided by Altmetric


Actions

    Link to this publication


Share