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Fluorescence, mechanical and swelling properties of chitosan-genipin and chitosan-genipin-PVP hydrogels

Lookup NU author(s): Durda Vukajlovic, Dr Oana Bretcanu, Dr Julie Parker, Dr Katarina Novakovic

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Abstract

Chitosan (Cht) is extensively studied biomaterial, due to its biocompatibility and biodegradability. Addition of genipin (Gen) to chitosan hydrogels produces cross-links which strengthen the hydrogel network and as added bonus induce fluorescence. At the same time, genipin, natural agent extracted from Gardenia fruit, has significantly lower toxicity, compared to other currently used substances. Polyvinylpyrrolidone (PVP) has been added to the hydrogels to further aid water absorption and enhance pore dispersion. The aim of this work is to determine the effect of genipin and PVP on the chitosan-genipin and chitosan-genipin-PVP hydrogels fluorescence, mechanical and swelling properties, relevant to prospective medical applications.


Publication metadata

Author(s): Vukajlovic D, Bretcanu O, Parker J, Novakovic K

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: 4th International Conference on Biomedical Polymers and Polymeric Biomaterials (ISBPPB 2018)

Year of Conference: 2018

Online publication date: 15/07/2018

Acceptance date: 08/03/2018

Publisher: International Society for Biomedical Polymers and Polymeric Biomaterials

URL: https://isbppb2018.org/


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