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Lookup NU author(s): Professor Colin Rees
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Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.Aim Medication may be used to manage discomfort during colonoscopy but practice varies. The relationship between medication use and comfort during colonoscopy was examined in the English Bowel Cancer Screening Programme. Methods Data related to patient comfort and medication use from all 113 316 examinations performed within the English Bowel Cancer Screening Programme between 1 January 2010 and 31 December 2012 were analysed. Comfort was rated on the five-point Modified Gloucester Comfort Scale: 1, no discomfort; 5, severe discomfort. Scores of 4 and 5 were considered to indicate significant discomfort. Correlations between the proportion of examinations associated with significant discomfort and the amounts of medication used by colonoscopists were assessed using Spearman's ρ. Logistic regression modelling examined the independent predictors of significant discomfort. Results Patients had a mean age of 65.7 years, and 58% were male. Examinations were performed by 290 endoscopists. In 91% of examinations, there was no significant discomfort reported during examination; however, there was considerable variation between individual colonoscopists (range 76.1-99.2%). Intravenous sedation and opiate analgesia were used during most examinations, but there was wide variation between colonoscopists, with a median (range) usage of 95.1% (4.1-100%) and 97.3% (5.6-100%), respectively. There was no association between the amount of sedation and analgesia used and significant discomfort (ρ<0.2). On multivariate analysis, significant discomfort was found to be more common among female individuals [odds ratio (OR)=2.0], on incomplete examinations (OR=6.7), and among patients with diverticulosis (OR=1.4). Conclusion There was wide variation in medication practice among English screening colonoscopists, but this was unrelated to the occurrence of significant discomfort.
Author(s): Ball AJ, Rees CJ, Corfe BM, Riley SA
Publication type: Article
Publication status: Published
Journal: European Journal of Gastroenterology and Hepatology
Year: 2015
Volume: 27
Issue: 6
Pages: 741-746
Print publication date: 01/12/2015
Online publication date: 01/06/2015
Acceptance date: 05/03/2015
ISSN (print): 0954-691X
ISSN (electronic): 1473-5687
Publisher: Lippincott Williams and Wilkins
URL: https://doi.org/10.1097/MEG.0000000000000360
DOI: 10.1097/MEG.0000000000000360
PubMed id: 25874595
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