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Lookup NU author(s): Dr Ana Ferreira-DuarteORCiD, Thalea Turowski, Dr Piergiorgio GentileORCiD
This is the authors' accepted manuscript of a review published in its final definitive form in 2019. For re-use rights please refer to the publishers terms and conditions.
The coatings application onto medical devices has experienced a continuous growth in the last few years. Medical device coating market is expected to grow at a CAGR of 5.16% to reach USD 10 million by 2023 due to the increasing geriatric population and the growing demand for continuous innovation. Layer-by-Layer (LbL) assembly represents a versatile method to modify the surface properties, in order to control cell interaction and thus enhance biological functions. Furthermore, LbL is environmentally friendly, able to coat all types of surfaces with the creation of homogenous film and to include and control the release of biomolecules/drugs. This feature review provides a critical overview on recent progresses in functionalizing materials by LbL assembly for bone regeneration and disorder treatment. An overview of emerging and visionary opportunities on LbL technologies and further combination with other existing methods used in biomedical field, are also discussed to evidence the new challenges and potential developments in bone regenerative medicine.
Author(s): Ferreira AM, Tonda-Turo C, Mancuso E, Gentile P
Publication type: Review
Publication status: Published
Journal: Nanomedicine: Nanotechnology, Biology and Medicine
Year: 2019
Volume: 19
Pages: 22-38
Print publication date: 01/07/2019
Online publication date: 17/04/2019
Acceptance date: 04/04/2019
ISSN (print): 1549-9634
ISSN (electronic): 1549-9642
URL: https://doi.org/10.1016/j.nano.2019.03.009
DOI: 10.1016/j.nano.2019.03.009
