Lookup NU author(s): James Holland,
Professor David Deehan
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© 2019 Elsevier B.V. Background: The aim of this study was to identify minimal clinically important difference (MCID), minimal important change (MIC) and minimal detectable change (MDC) for the Short Form (SF-) 12 physical and mental component summary (PCS, MCS) scores after total knee arthroplasty (TKA) using an anchor based methodology. Methods: During a 10-year period, 2589 TKA were performed. SF-12 PCS and MCS scores were recorded preoperatively and at one year postoperatively. At one year, patients were asked “How much did the knee replacement surgery improve the quality of your life?” Their response was recorded as: a great improvement, moderate improvement, little improvement, no improvement at all, or the quality of my life is worse. Patients recording a little (n = 211) and no (n = 115) were used to calculate the MCID and the MIC. The MDC90 was calculated using distribution based methods for the whole cohort. Results: The MCID was 1.8 (p = 0.04) for the PCS and 1.5 (p = 0.33) for the MCS score. The MIC was 2.7 (p = 0.04) for the PCS and − 1.4 (p = 0.17) for the MCS score. The MDC90 was 8.9 for the PCS and 13.8 for the MCS score. Conclusion: The MCID for the PCS can be used to compare the outcomes between groups, and the MIC can be used to ensure that a clinical difference has been observed for a cohort of patients. The values for the MDC90 can be used to assess whether or not an individual patient has experienced a change.
Author(s): Clement ND, Weir D, Holland J, Gerrand C, Deehan DJ
Publication type: Article
Publication status: Published
Pages: Epub ahead of print
Online publication date: 17/05/2019
Acceptance date: 30/04/2019
ISSN (print): 0968-0160
ISSN (electronic): 1873-5800
Publisher: Elsevier B.V.
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