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Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4

Lookup NU author(s): Stephanie Myers, Duncan Miller, Dr Lauren Molyneux, Dr Mercedeh Arasta, Dr Ruth Bawn, Dr Tim Blackburn, Dr Noel Edwards, Professor Jane Endicott, Professor Bernard Golding, Professor Roger Griffin, Dr Ian Hardcastle, Dr Suzannah Harnor, Amy Heptinstall, Dr Mathew Martin, Nick Martin, Emeritus Professor Herbie Newell, Tristan Reuillon, Dr Laurent Rigoreau, Huw Thomas, Julie Tucker, Lan Wang, Professor Martin Noble, Professor Steve Wedge, Dr Celine Cano

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Author(s): Myers SM, Miller DC, Molyneux L, Arasta M, Bawn RH, Blackburn TJ, Cook SJ, Edwards N, Endicott JA, Golding BT, Griffin RJ, Hammonds T, Hardcastle IR, Harnor SJ, Heptinstall AB, Lochhead PA, Martin MP, Martin NC, Newell DR, Owen PJ, Pang LC, Reuillon T, Rigoreau LJM, Thomas HD, Tucker JA, Wang L-Z, Wong A-C, Noble MEM, Wedge SR, Cano C

Publication type: Article

Publication status: Published

Journal: European Journal of Medicinal Chemistry

Year: 2019

Volume: 178

Pages: 530-543

Print publication date: 15/09/2019

Online publication date: 25/05/2019

Acceptance date: 20/05/2019

Date deposited: 22/07/2019

ISSN (print): 0223-5234

ISSN (electronic): 1768-3254

Publisher: Elsevier Masson SAS

URL: https://doi.org/10.1016/j.ejmech.2019.05.057

DOI: 10.1016/j.ejmech.2019.05.057


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