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Age-Specific Incidence Rates for Norovirus in the Community and Presenting to Primary Healthcare Facilities in the United Kingdom

Lookup NU author(s): Professor Sarah O'Brien

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Abstract

© 2016 The Author. In a prospective, population-based cohort study and a study of primary-healthcare consultations, we had a rare opportunity to estimate age-specific rates of norovirus-associated infectious intestinal disease in the United Kingdom. Rates in children aged <5 years were significantly higher than those for other age groups in the community (142.6 cases per 1000 person-years [95% confidence interval {CI}, 99.8-203.9] vs 37.6 [95% CI, 31.5-44.7]) and those for individuals presenting to primary healthcare (14.4 cases per 1000 person-years [95% CI, 8.5-24.5] vs 1.4 [95% CI,. 9-2.0]). Robust incidence estimates are crucial for vaccination policy makers. This study emphasises the impact of norovirus-associated infectious intestinal disease, especially in children aged <5 years.

Publication metadata

Author(s): O'Brien SJ, Donaldson AL, Iturriza-Gomara M, Tam CC

Publication type: Article

Publication status: Published

Journal: Journal of Infectious Diseases

Year: 2016

Volume: 213

Issue: suppl 1

Pages: S15-S18

Print publication date: 01/02/2019

Online publication date: 19/12/2015

Acceptance date: 01/01/1900

ISSN (print): 0022-1899

ISSN (electronic): 1537-6613

Publisher: Oxford University Press

URL: https://doi.org/10.1093/infdis

DOI: 10.1093/infdis/jiv411

PubMed id: 26744427

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