Lookup NU author(s): Professor Anne Dickinson,
Dr Shaheda Ahmed
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© 2019, Mary Ann Liebert, Inc., publishers.Over the past decade, there has been a significant increase in preclinical development and clinical use of approved nanomedicines. The nanomedicinal field represents a wide variety of products including early diagnostics such as in vivo imaging, medicinal devices, and innovative therapeutics. Nanomedicines exhibit unique physiochemical properties compared with their nonnanoformulated counterparts; however, clinical reports of moderate-to-severe allergic, anaphylaxis, and hypersensitivity reactions raise major concerns with regard to nanomedicine immunotoxicity. This review summarizes some of the main applications of nanomedicines, safety, and immunotoxicity implications and current testing strategies.
Author(s): Dickinson AM, Godden JM, Lanovyk K, Ahmed SS
Publication type: Review
Publication status: Published
Journal: Applied In Vitro Toxicology
Online publication date: 17/09/2019
Acceptance date: 02/04/2016
ISSN (print): 2332-1512
ISSN (electronic): 2332-1539
Publisher: Mary Ann Liebert Inc.