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Ammonium transceptors: Novel regulators of fungal development

Lookup NU author(s): Professor Bert van den Berg, Siobhan Lister, Dr Julian Rutherford

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

Transceptors are nutrient transporters that act as receptors to regulate downstream signalling pathways. Ammonium transceptors regulate fungal morphology in response to limiting levels of ammonium, which is utilised as a nitrogen source. Few studies have addressed to what extent ammonium transceptors are conserved in pathogenic fungi. Plant and animal fungal pathogens undergo a variety of developmental transitions during infection and work on some plant fungal pathogens establishes the importance of ammonium transporters during host infection [1, 2]. More widespread studies are needed to determine if ammonium transceptors have a general role in regulating the virulence of fungal pathogens.


Publication metadata

Author(s): van den Berg B, Lister S, Rutherford JC

Publication type: Article

Publication status: Published

Journal: PLoS Pathogens

Year: 2019

Volume: 15

Issue: 11

Online publication date: 07/11/2019

Acceptance date: 25/09/2019

Date deposited: 12/11/2019

ISSN (print): 1553-7366

ISSN (electronic): 1553-7374

Publisher: Public Library of Science

URL: https://doi.org/10.1371/journal.ppat.1008059

DOI: 10.1371/journal.ppat.1008059

PubMed id: 31697784


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