Lookup NU author(s): Lewis Grozinger,
Dr Harold Fellermann,
Dr Paolo Zuliani,
Dr Angel Goni-Moreno
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Synthetic biology uses living cells as the substrate for performing human-defined computations. Many current implementations of cellular computing are based on the “genetic circuit” metaphor, an approximation of the operation of silicon-based computers. Although this conceptual mapping has been relatively successful, we argue that it fundamentally limits the types of computation that may be engineered inside the cell, and fails to exploit the rich and diverse functionality available in natural living systems. We propose the notion of “cellular supremacy” to focus attention on domains in which biocomputing might offer superior performance over traditional computers. We consider potential pathways toward cellular supremacy, and suggest application areas in which it may be found.
Author(s): Grozinger L, Amos M, Gorochowski TE, Carbonell P, Oyarzún DA, Stoof R, Fellermann H, Zuliani P, Tas H, Goñi-Moreno A
Publication type: Article
Publication status: Published
Journal: Nature Communications
Print publication date: 20/11/2019
Online publication date: 20/11/2019
Acceptance date: 29/10/2019
ISSN (electronic): 2041-1723
Publisher: Nature Publishing
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