Lookup NU author(s): Dr Christopher Nile
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).
© 2018 Elsevier Inc. Management of fungal biofilms represents a significant challenge to healthcare. As a preventive approach, minimizing adhesion between indwelling medical devices and microorganisms would be an important step forward. This study investigated the anti-fouling capacity of engineered nanoscale topographies to the pathogenic yeast Candida albicans. Highly ordered arrays of nano-pit topographies were shown to significantly reduce the physical adherence capacity of C. albicans. This study shows a potential of nanoscale patterns to inhibit and prevent pathogenic biofilm formation on biomedical substrates.
Author(s): Alalwan H, Nile CJ, Rajendran R, McKerlie R, Reynolds P, Gadegaard N, Ramage G
Publication type: Article
Publication status: Published
Journal: Nanomedicine: Nanotechnology, Biology, and Medicine
Print publication date: 01/04/2018
Online publication date: 02/02/2018
Acceptance date: 21/01/2018
Date deposited: 24/02/2020
ISSN (print): 1549-9634
ISSN (electronic): 1549-9642
Publisher: Elsevier Inc.
PubMed id: 29408656
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