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Lookup NU author(s): Sanjay PandanaboyanaORCiD
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Background: This study compared epidural analgesia with local anesthetic administration via transabdominal wall catheters (TAWC), to determine the effect on perioperative outcomes in pancreatic surgery. Materials and methods: A retrospective review of patients undergoing open pancreatic surgery at Auckland City Hospital from 2015 to 2018 was undertaken. Data collected included patient demographics, type of perioperative analgesia, intravenous fluid and vasopressor use, length of high dependency unit stay, postoperative complications, and length of hospital stay. Results: Seventy-two patients underwent pancreatic surgery, of which 47 had epidural analgesia and 25 TAWC. The median age was 64 y (range 29-85). Failure of analgesia method occurred in 45% of epidural patients and 28% of TAWC patients (P = 0.209). There was no significant difference in volume of intravenous fluid given or need for vasopressors in the first 3 postoperative days, length of high dependency unit stay (median 1 d, P = 0.2836), rates of postoperative pancreatic fistula (32% versus 40%, P = 0.6046), postoperative complications (38% versus 20%, P = 0.183), or mortality (0.04% versus 0.04%, P = 1.0). Conclusions: Epidural analgesia and TAWC may have comparable perioperative outcomes in patients undergoing pancreatic surgery. Further randomized studies with a larger cohort of patients are warranted to identify the best postoperative analgesic method in patients undergoing pancreatic resection.
Author(s): Perrin J, Ratnayake R, Wells C, Windsor JA, Loveday B, Maclennan N, Lindsay H, Pandanaboyana S
Publication type: Article
Publication status: Published
Journal: Journal of Surgical Research
Year: 2021
Volume: 259
Pages: 473-479
Print publication date: 01/03/2021
Online publication date: 25/10/2020
Acceptance date: 05/10/2020
ISSN (print): 0022-4804
ISSN (electronic): 1095-8673
Publisher: Elsevier
URL: https://doi.org/10.1016/j.jss.2020.09.005
DOI: 10.1016/j.jss.2020.09.005
PubMed id: 33070995
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