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Lookup NU author(s): Dr Simon DohertyORCiD, Dr Julian Knight, Dr Paul Waddell, Dr Corinne Wills, Dr Casey Dixon
This is the authors' accepted manuscript of an article that has been published in its final definitive form by Wiley-VCH Verlag GmbH & Co. KGaA, 2021.
For re-use rights please refer to the publisher's terms and conditions.
The Noyori‐Ikariya (arene)Ru(II)/TsDPEN precatalyst has been anchored to amorphous silica and DAVISIL through the η6‐coordinated arene ligand via a straightforward synthesis and the derived systems, (arene)Ru(II)/TsDPEN@silica and (arene)Ru(II)/TsDPEN@DAVISIL, form highly efficient catalysts for the asymmetric transfer hydrogenation of a range of electron‐rich and electron‐poor aromatic ketones, giving good conversion and excellent ee's under mild reaction conditions. Moreover, catalyst generated in situ immediately prior to addition of substrate and hydrogen donor, by reaction of silica‐supported [(arene)RuCl2]2 with (S,S)‐TsDPEN, was as efficient as that generated from its preformed counterpart [(arene)Ru{(S,S)‐TsDPEN}Cl]@silica. Gratifyingly, the initial TOFs (up to 1085 h−1) and ee's (96–97 %) obtained with these catalysts either rivalled or outperformed those previously reported for catalysts supported by either silica or polymer immobilized through one of the nitrogen atoms of TsDPEN. While the high ee's were also maintained during recycle studies, the conversion dropped steadily over the first three runs due to gradual leaching of the ruthenium.
Author(s): Doherty S, Knight JG, Alshaikh H, Wilson J, Waddell PG, Wills C, Dixon CM
Publication type: Article
Publication status: Published
Journal: European Journal of Inorganic Chemistry
Year: 2021
Volume: 2021
Issue: 3
Pages: 226-235
Print publication date: 22/01/2021
Online publication date: 02/12/2020
Acceptance date: 02/12/2020
Date deposited: 28/01/2021
ISSN (electronic): 1099-0682
Publisher: Wiley-VCH Verlag GmbH & Co. KGaA
URL: .doi.org/10.1002/ejic.202000948
DOI: 10.1002/ejic.202000948
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