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Point of care detection of COVID-19: Advancement in biosensing and diagnostic methods

Lookup NU author(s): Dr Yen Nee Tan

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Abstract

The recent outbreak of COVID-19 has created much inconvenience and fear that the virus can seriously affect humans, causing health hazards and death. This pandemic has created much worry and as per the report by World Health Organization (WHO), more than 43 million individuals in 215 countries and territories were affected. People around the world are still struggling to overcome the problems associated with this pandemic. Of all the available methods, reverse-transcriptase polymerase chain reaction (RT-PCR) has been widely practiced for the pandemic detection even though several diagnostic tools are available having varying accuracy and sensitivity. The method offers many advantages making it a life-saving tool, but the method has the limitation of transporting to the nearest pathology lab, thus limiting its application in resource limited settings. This has a risen a crucial need for point-of-care devices for on-site detection. In this venture, biosensors have been used, since they can be applied immediately at the point-of-care. This review will discuss about the available diagnostic methods and biosensors for COVID-19 detection.


Publication metadata

Author(s): Suleman S, Shukla SK, Malhotra N, Bukkitgar SD, Shetti NP, Pilloton R, Narang J, Tan YN, Aminabhavi TM

Publication type: Review

Publication status: Published

Journal: Chemical Engineering Journal

Year: 2021

Volume: 414

Online publication date: 31/01/2021

Acceptance date: 25/01/2021

ISSN (electronic): 1385-8947

URL: https://doi.org/10.1016/j.cej.2021.128759

DOI: 10.1016/j.cej.2021.128759


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