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An overview of N-heterocyclic carbenes

Lookup NU author(s): Dr Matt HopkinsonORCiD

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Abstract

The successful isolation and characterization of an N-heterocyclic carbene in 1991 opened up a new class of organic compounds for investigation. From these beginnings as academic curiosities, N-heterocyclic carbenes today rank among the most powerful tools in organic chemistry, with numerous applications in commercially important processes. Here we provide a concise overview of N-heterocyclic carbenes in modern chemistry, summarizing their general properties and uses and highlighting how these features are being exploited in a selection of pioneering recent studies. © 2014 Macmillan Publishers Limited.

Publication metadata

Author(s): Hopkinson MN, Richter C, Schedler M, Glorius F

Publication type: Review

Publication status: Published

Journal: Nature

Year: 2014

Volume: 510

Issue: 7506

Pages: 485-496

Online publication date: 25/06/2014

Acceptance date: 09/04/2014

ISSN (print): 0028-0836

ISSN (electronic): 1476-4687

Publisher: Nature Publishing Group

URL: https://doi.org/10.1038/nature13384

DOI: 10.1038/nature13384

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