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Cohort Profile Update: The British Regional Heart Study 1978–2018: 40-years of follow-up of older British men

Lookup NU author(s): Dr Rachel Kimble, Gillian McLellan, Professor John Mathers, Professor Sheena Ramsay

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

Key Features The British Regional Heart Study (BRHS) consists of an all-male cohort of 7735 participants aged 40-59-years first recruited in 1978-80 and followed-up over 40-years to 2018. The original focus of the BRHS was to investigate regional variations in cardiovascular disease (CVD) mortality across Britain, but the objectives widened to examine other key health outcomes related to CVD and associated with healthy ageing, such as physical function, disability, frailty, dental health, malnutrition, and sarcopenia. The latest physical examination (40-year follow-up) of the cohort conducted in 2018, hosted 667 men and 1009 responded to postal questionnaires aged 78-99-years. This follow-up enhances prospective data at very advanced ages by building on the previous examination in 2010-12 at 71-92-years. The new measures conducted within this cohort’s 40-year follow-up include extended objective and subjective oral health measures, subjective appetite and malnutrition measures, and anthropometric measures associated with lower body extremity muscle mass. The BRHS has maintained existing collaborations and remains open to new collaborative projects. Please contact Lucy Lennon [l.lennon@ucl.ac.uk] for more details.


Publication metadata

Author(s): Kimble R, McLellan G, Lennon LT, Papacosta AO, Mathers JC, Wannamethee SG, Whincup PH, Ramsay SE

Publication type: Article

Publication status: Published

Journal: International Journal of Epidemiology

Year: 2022

Issue: ePub ahead of Print

Online publication date: 03/06/2022

Acceptance date: 19/05/2022

Date deposited: 01/06/2022

ISSN (print): 0300-5771

ISSN (electronic): 1464-3685

Publisher: Oxford University Press

URL: https://doi.org/10.1093/ije/dyac122

DOI: 10.1093/ije/dyac122


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Funding

Funder referenceFunder name
13_CM08
FR3–80
FR5- 166
FR10-281
FR9-533690
G1002391
PG/13/41/30304
R396_1114
R592_0515
R592_0717
PG/13/86/30546
R03 DE028505-02
RG/08/013/25942
RG/13/16/30528
RG/19/4/34452

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