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Natural experiments for the evaluation of place-based public health interventions: a methodology scoping review

Lookup NU author(s): Dr Morgan Beeson, Professor Falko Sniehotta

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

Copyright © 2023 Albers, Rinaldi, Brown, Mason, d'Apice, McGill, McQuire, Craig, Laverty, Beeson, Campbell, Egan, Gibson, Fuller, Dillon, Taylor-Robinson, Jago, Tilling, Barr, Sniehotta, Hickman, Millett and de Vocht.Introduction: Place-based public health evaluations are increasingly making use of natural experiments. This scoping review aimed to provide an overview of the design and use of natural experiment evaluations (NEEs), and an assessment of the plausibility of the as-if randomization assumption. Methods: A systematic search of three bibliographic databases (Pubmed, Web of Science and Ovid-Medline) was conducted in January 2020 to capture publications that reported a natural experiment of a place-based public health intervention or outcome. For each, study design elements were extracted. An additional evaluation of as-if randomization was conducted by 12 of this paper's authors who evaluated the same set of 20 randomly selected studies and assessed ‘as-if ' randomization for each. Results: 366 NEE studies of place-based public health interventions were identified. The most commonly used NEE approach was a Difference-in-Differences study design (25%), followed by before-after studies (23%) and regression analysis studies. 42% of NEEs had likely or probable as-if randomization of exposure (the intervention), while for 25% this was implausible. An inter-rater agreement exercise indicated poor reliability of as-if randomization assignment. Only about half of NEEs reported some form of sensitivity or falsification analysis to support inferences. Conclusion: NEEs are conducted using many different designs and statistical methods and encompass various definitions of a natural experiment, while it is questionable whether all evaluations reported as natural experiments should be considered as such. The likelihood of as-if randomization should be specifically reported, and primary analyses should be supported by sensitivity analyses and/or falsification tests. Transparent reporting of NEE designs and evaluation methods will contribute to the optimum use of place-based NEEs.


Publication metadata

Author(s): Albers PN, Rinaldi C, Brown H, Mason KE, d'Apice K, McGill E, McQuire C, Craig P, Laverty AA, Beeson M, Campbell M, Egan M, Gibson M, Fuller M, Dillon A, Taylor-Robinson D, Jago R, Tilling K, Barr B, Sniehotta FF, Hickman M, Millett CJ, de Vocht F

Publication type: Review

Publication status: Published

Journal: Frontiers in Public Health

Year: 2023

Volume: 11

Online publication date: 22/06/2023

Acceptance date: 08/06/2023

ISSN (electronic): 2296-2565

Publisher: Frontiers Media SA

URL: https://doi.org/10.3389/fpubh.2023.1192055

DOI: 10.3389/fpubh.2023.1192055


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