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Assembly of pore proteins on gold electrodes

Lookup NU author(s): Dr Qi Hong, Professor Jeremy Lakey

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Abstract

Protein-protein interactions at the cell surface are important in the activity of bacterial toxins such as colicins. We have developed methods to study these events using tethered lipid bilayers, which can be probed by impedance spectroscopy and surface plasmon resonance. Recently we have attached the receptor proteins directly to gold electrodes and this offers new possibilities for measuring protein-protein interactions on solid supports.


Publication metadata

Author(s): Hong Q, Terrettaz S, Ulrich WP, Vogel H, Lakey JH

Publication type: Article

Publication status: Published

Journal: Biochemical Society Transactions

Year: 2001

Volume: 29

Issue: 4

Pages: 578-582

ISSN (print): 0300-5127

ISSN (electronic): 1470-8752

Publisher: Portland Press Ltd.

URL: http://dx.doi.org/10.1042/BST0290578

DOI: 10.1042/BST0290578


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