Lookup NU author(s): Dr Qi Hong,
Professor Jeremy Lakey
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Protein-protein interactions at the cell surface are important in the activity of bacterial toxins such as colicins. We have developed methods to study these events using tethered lipid bilayers, which can be probed by impedance spectroscopy and surface plasmon resonance. Recently we have attached the receptor proteins directly to gold electrodes and this offers new possibilities for measuring protein-protein interactions on solid supports.
Author(s): Hong Q, Terrettaz S, Ulrich WP, Vogel H, Lakey JH
Publication type: Article
Publication status: Published
Journal: Biochemical Society Transactions
ISSN (print): 0300-5127
ISSN (electronic): 1470-8752
Publisher: Portland Press Ltd.
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