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Lookup NU author(s): Professor Malcolm Young,
Dr Jack Scannell
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Studies of the effects of brain lesions on behaviour have informed brain sciences for more than 100 years. Paradoxical results from some experiments, however, contradict widely accepted logic for imputing function to structure, including the 'gold standard'; double dissociation. Orienting systems have produced clear examples of paradoxical lesion effects and provide the opportunity to identify reliable inference for imputing function. Our models reproduced the experimental effects. Analysis of the models demonstrated why single and double dissociation studies do not yield reliable conclusions, but suggested more reliable methods for understanding the delegation of functions to neuroanatomical structures in large-scale neural networks.
Author(s): Young MP, Hilgetag C, Scannell JW
Publication type: Article
Publication status: Published
Print publication date: 01/06/1999
ISSN (print): 0925-2312
ISSN (electronic): 1872-8286
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