Toggle Main Menu Toggle Search

Open Access padlockePrints

Models of paradoxical lesion effects and rules of inference for imputing function to structure in the brain

Lookup NU author(s): Professor Malcolm Young, Dr Jack Scannell

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Abstract

Studies of the effects of brain lesions on behaviour have informed brain sciences for more than 100 years. Paradoxical results from some experiments, however, contradict widely accepted logic for imputing function to structure, including the 'gold standard'; double dissociation. Orienting systems have produced clear examples of paradoxical lesion effects and provide the opportunity to identify reliable inference for imputing function. Our models reproduced the experimental effects. Analysis of the models demonstrated why single and double dissociation studies do not yield reliable conclusions, but suggested more reliable methods for understanding the delegation of functions to neuroanatomical structures in large-scale neural networks.


Publication metadata

Author(s): Young MP, Hilgetag C, Scannell JW

Publication type: Article

Publication status: Published

Journal: Neurocomputing

Year: 1999

Volume: 26-27

Pages: 933-938

Print publication date: 01/06/1999

ISSN (print): 0925-2312

ISSN (electronic): 1872-8286

Publisher: Elsevier

URL: http://dx.doi.org/10.1016/S0925-2312(99)00012-0

DOI: 10.1016/S0925-2312(99)00012-0


Altmetrics

Altmetrics provided by Altmetric


Actions

Find at Newcastle University icon    Link to this publication


Share