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Dental manifestations in severe combined immunodeficiency following bone marrow transplantation

Lookup NU author(s): Dr Ben Cole, Dr Mario Abinun

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Abstract

Severe combined immunodeficiency (SCID) is a rare primary immunodeficiency disorder with an estimated overall frequency of 1 in 75,000 live births. Bone marrow transplantation is the only curative treatment available. Using T cell-depleted HLA non-identical bone marrow requires preconditioning with a short course of cytotoxic chemotherapy. We report severe dental developmental anomalies in three such patients under longterm follow up.

Publication metadata

Author(s): Cole BOI, Welbury RR, Bond E, Abinun M

Publication type: Article

Publication status: Published

Journal: Bone Marrow Transplantation

Year: 2000

Volume: 25

Issue: 9

Pages: 1007-1009

Print publication date: 01/01/2000

ISSN (print): 0268-3369

ISSN (electronic): 1476-5365

Publisher: Nature Publishing Group

URL: http://dx.doi.org/10.1038/sj.bmt.1702382

DOI: 10.1038/sj.bmt.1702382

PubMed id: 10800072

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