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Monoclonal antibodies useful in sensitive immunoassays for aldicarb in either laboratory or the field

Lookup NU author(s): Dr Lai Siew, Dr Larry Winger, Julia Spoors, John Dessi, Emeritus Professor Colin Self

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Abstract

Although polyclonal antisera have been used for immunodiagnostic measurement of aldicarb, both as components of commercial kits and as stand-alone products, no monoclonal antibody (MAb) reactive to this carbamate pesticide has yet been described. We have generated two MAbs with specificity to aldicarb, which function in our prototypic field immunoassays to identify this chemical in water samples. Further exploitation of these inherently stable immunoreagents should be valuable for point-of-need testing for the presence of aldicarb.


Publication metadata

Author(s): Siew LK, Winger LA, Spoors JA, Dessi JL, Jennens L, Self CH

Publication type: Article

Publication status: Published

Journal: International Journal of Environmental Analytical Chemistry

Year: 2003

Volume: 83

Issue: 5

Pages: 417-426

ISSN (print): 0306-7319

ISSN (electronic): 1026-7468

Publisher: Taylor & Francis

URL: http://dx.doi.org/10.1080/0306731031000099819

DOI: 10.1080/0306731031000099819


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