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Hyperammonaemic coma post-renal transplantation

Lookup NU author(s): Professor John Sayer, Bryon Jaques


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Hyperammonaemia is commonly associated with encephalopathy secondary to hepatic dysfunction, but may also be secondary to cases of inherited metabolic defects of urea synthesis. Additional causes of hyperammonaemia are exceptionally rare, but do occur in the context of urinary tract abnormalities and urinary infections with urease-positive bacteria. We describe a case of severe hyperammonaemia leading to coma following a urinary leak post-renal transplantation, where liver function tests were entirely normal.

Publication metadata

Author(s): Sayer JA, Bhatti AA, Jaques B, Nesbitt I

Publication type: Article

Publication status: Published

Journal: Clinical Intensive Care

Year: 2003

Volume: 14

Issue: 1-2

Pages: 37-40

ISSN (print): 0956-3075

ISSN (electronic):

Publisher: Informa Healthcare


DOI: 10.1080/09563070310001612826


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