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Malignant tumours of the minor salivary glands - A 20 year review

Lookup NU author(s): Dr Clive Kelly, Neil McLean

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Abstract

The UK incidence of malignant disease of the minor salivary glands is only 0.6 per million per year. The tumours have a varied histology, can present in any age group and are frequently advanced if located in the sinonasal cavities. In a 20-year review of 21 patients treated for minor salivary gland malignancy in a single institution, it was found that mucoepidermoid tumours were more common in the oral cavity and adenoid cystic carcinomas in the sinonasal tract (p=0.002). Outcome was variable with sinonasal and adenoid cystic carcinoma having a poorer outcome. Kaplan-Meier curves showed that oral tumours had a higher probability of long term survival. Radical surgery with reconstruction and post-operative adjuvant radiotherapy was effective in achieving loco-regional control. There were no local recurrences within 5 years and three after 5 years. Five patients developed metastatic disease within 10 years and a further two after 10 years. Late recurrences occurred and survival was mainly determined by the presence of systemic disease. © 2004 The British Association of Plastic Surgeons. Published by Elsevier Ltd. All rights reserved.

Publication metadata

Author(s): Strick MJ, Kelly C, Soames JV, McLean NR

Publication type: Review

Publication status: Published

Journal: British Journal of Plastic Surgery

Year: 2004

Volume: 57

Issue: 7

Pages: 624-631

ISSN (print): 0007-1226

ISSN (electronic):

URL: http://dx.doi.org/10.1016/j.bjps.2004.04.017

DOI: 10.1016/j.bjps.2004.04.017

PubMed id: 15380695

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