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A grid-based system for microbial genome comparison and analysis

Lookup NU author(s): Professor Anil Wipat, Dr Matthew Pocock, Professor Pete Lee, Professor Paul Watson, Dr Keith Flanagan

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Abstract

Genome comparison and analysis can reveal the structures and functions of genome sequences of different species. As more genomes are sequenced, genomic data sources are rapidly increasing such that their analysis is beyond the processing capabilities of most research institutes. The Grid is a powerful solution to support large-scale genomic data processing and genome analysis. This paper presents the Microbase project that is developing a Grid-based system for genome comparison and analysis, and discusses the first implementation of the system (called MicrobaseLite). MicrobaseLite uses a scalable computing environment to support computationally intensive microbial genome comparison and analysis, employing state-of-the-art technologies of Web Services, notification, comparative genomics and parallel computing. Microbase will support not only system-defined genome comparison and analysis but also user-defined, remotely conceived genome analysis. © 2005 IEEE.


Publication metadata

Author(s): Sun Y, Wipat A, Pocock M, Lee PA, Watson P, Flanagan K, Worthington JT

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: IEEE International Symposium on Cluster Computing and the Grid, CCGrid 2005

Year of Conference: 2005

Number of Volumes: 2

Pages: 977-984

Publisher: IEEE

URL: http://dx.doi.org/10.1109/CCGRID.2005.1558667

DOI: 10.1109/CCGRID.2005.1558667

Library holdings: Search Newcastle University Library for this item

ISBN: 0780390741


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