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Lookup NU author(s): Dr Sally Stephens,
Professor Raj Kalaria,
Dr Clive Ballard
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OBJECTIVES: To determine the relationship between mild vascular cognitive impairment (mVCI) and functional disability in older stroke survivors without dementia. DESIGN: Cohort study. SETTING: Stroke patients from representative hospital-based stroke registers. PARTICIPANTS: Three hundred thirty-nine stroke survivors without dementia, aged 75 and older. MEASUREMENTS: Neuropsychological assessments were completed 3 months poststroke. Activities of daily living (ADLs) were evaluated using the Bristol scale. Operationalized criteria, including cognitive impairment no dementia (CIND), were applied for mVCI. RESULTS: Significant impairments of ADLs were evident in mVCI (CIND vs no CIND; basic care: z = 3.2; P = .001, intermediate care: z = 3.6; P < .001, complex management: z = 4.5; P < .001) but varied according to the profile of cognitive impairments. Patients with attentional or global impairments had more severe functional disability than patients with isolated memory deficits, with an intermediate level of dysfunction in patients with executive impairments. CONCLUSION: The findings emphasize the importance of identifying early cognitive impairments to optimize rehabilitation, care planning, and secondary prevention of dementia in stroke patients. © 2005 by the American Geriatrics Society.
Author(s): Stephens S, Kenny RA, Rowan E, Kalaria RN, Bradbury M, Pearce R, Wesnes K, Ballard CG
Publication type: Article
Publication status: Published
Journal: Journal of the American Geriatrics Society
Print publication date: 01/01/2005
ISSN (print): 0002-8614
ISSN (electronic): 1532-5415
PubMed id: 15667385
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