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Mitochondrial disease in adults: A scale to monitor progression and treatment

Lookup NU author(s): Dr Andrew Schaefer, Dr Joanna Elson, Professor Bobby McFarland, Professor Patrick Chinnery, Professor Doug Turnbull

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Abstract

The natural history of mitochondrial diseases is poorly understood, limiting our ability to offer prognostic advice to patients or to evaluate therapy. One major obstacle to improving our understanding is the lack of a clinical rating scale to monitor the extensive clinical spectrum of mitochondrial disease. In this article, the authors describe the development and validation of a practical and semiquantitative rating scale, the Newcastle Mitochondrial Disease Adult Scale. Copyright © 2006 by AAN Enterprises, Inc.


Publication metadata

Author(s): Schaefer AM, Phoenix C, Elson JL, McFarland R, Chinnery PF, Turnbull DM

Publication type: Article

Publication status: Published

Journal: Neurology

Year: 2006

Volume: 66

Issue: 12

Pages: 1932-1934

ISSN (print): 0028-3878

ISSN (electronic): 1526-632X

Publisher: Lippincott Williams & Wilkins

URL: http://dx.doi.org/10.1212/01.wnl.0000219759.72195.41

DOI: 10.1212/01.wnl.0000219759.72195.41

PubMed id: 16801664


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