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Color discrimination in carriers of color deficiency

Lookup NU author(s): Lisa Purves, Dr Gabriele Jordan

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Abstract

Carriers of X-linked color vision deficiencies have previously been reported to exhibit mild abnormalities of color matching and discrimination. In a sample of 55 carriers of protan and deutan deficiencies and 55 age-matched normal controls, we measured chromatic discrimination along a red-green axis. We found that discrimination was impaired in the case of carriers of deutan deficiencies (which affect the middle-wave-sensitive cones of the retina), but was normal in the case of carriers of protan deficiencies (which affect the long-wave-sensitive cones). We argue that this result can be explained by the difference in the relative numbers of middle- and long-wave cones in heterozygous retinae: the imbalance of the two cone types is predicted to be much greater in the case of the deutan heterozygote than in the case of the protan heterozygote. In future studies it will be necessary to consider separately the two types of heterozygote. © 2006 Elsevier Ltd. All rights reserved.


Publication metadata

Author(s): Hood SM, Mollon JD, Purves L, Jordan G

Publication type: Article

Publication status: Published

Journal: Vision Research

Year: 2006

Volume: 46

Issue: 18

Pages: 2894-2900

ISSN (print): 0042-6989

ISSN (electronic): 1878-5646

Publisher: Pergamon

URL: http://dx.doi.org/10.1016/j.visres.2006.02.028

DOI: 10.1016/j.visres.2006.02.028

PubMed id: 16690099


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Funding

Funder referenceFunder name
058711/Z/99/LA/RA/ADWellcome Trust

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