Toggle Main Menu Toggle Search

Open Access padlockePrints

Allelic variation of a functional polymorphism in the serotonin transporter gene and depression in Parkinson's disease

Lookup NU author(s): Professor David Burn, Dr Liesl Allcock, Dr John Davison, Professor Patrick Chinnery

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Abstract

A genetic susceptibility to depression in PD, acting via the serotonergic system, has been suggested. We examined the influence of allelic variation (L/S) in a functional polymorphism in the serotonin transporter (5-HTTLPR) gene upon mood in 108 PD patients and 82 controls. Using a logistic regression model we found no evidence for an association between 5-HTTLPR genotypes, or the presence of the S allele, and depression. © 2006 Elsevier Ltd. All rights reserved.


Publication metadata

Author(s): Burn DJ, Tiangyou W, Allcock LM, Davison J, Chinnery PF

Publication type: Article

Publication status: Published

Journal: Parkinsonism & Related Disorders

Year: 2006

Volume: 12

Issue: 3

Pages: 139-141

ISSN (print): 1353-8020

ISSN (electronic): 1873-5126

Publisher: Elsevier

URL: http://dx.doi.org/10.1016/j.parkreldis.2005.11.005

DOI: 10.1016/j.parkreldis.2005.11.005

PubMed id: 16459126


Altmetrics

Altmetrics provided by Altmetric


Share